This phenomenon is termed peripheral sensitization ... This phenomenon is termed central sensitization. Neuropathic pain may be ongoing (e.g., burning pain), paroxysmal (e.g., electrical shock ...

Neuropathic pain is associated with a number of protein modifications in the central and peripheral nervous systems. Animal models of neuropathic pain can reflect human conditions after nerve injury.

Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around four in every 10 patients treated with these drugs, suggests a pooled data analysis of ...

Under this condition, which can result from traumatic injuries, infections, metabolic problems, or could be inherited due to ...

The central nervous system (CNS) has very limited capacity to regenerate after ... Some peripheral neuropathies involving SCs include Charcot-Marie-Tooth disease (CMT), Guillain-Barré syndrome, ...

XT-150 is under development for the treatment of peripheral neuropathic pain-lumbar radiculopathy, central neuropathic pain, multiple sclerosis, facet syndrome, osteoarthritis, osteoarthritis pain, ...

The stimulus-dependent pain is also a result of the peripheral and central changes. The cardinal features of classical neuropathic pain in the skin, such as seen in diabetes and in post-herpetic ...

Peripheral nerve injuries arising from trauma or disease can lead to sensory and motor deficits and neuropathic pain. Despite the purported ability of the peripheral ... White matter tracts in the ...

Around 4 in every 10 cancer patients taking chemotherapy are affected with severe peripheral nerve pain (neuropathy). Platinum-based drugs like taxanes and lung cancer are linked to higher rates ...

Worldwide, cancer chemotherapy is linked to persistent severe peripheral nerve pain (neuropathy) for around 4 in every 10 patients treated with these drugs, suggests a pooled data analysis of the ...