这篇综述聚焦癌症免疫中 cGAS-STING 通路，深入剖析其激活免疫反应、发挥抗肿瘤作用的机制，探讨在癌症治疗中的应用、STING 激动剂的研发进展，分析面临的挑战，为癌症免疫治疗提供新思路，文章发表在《Journal of Hematology & Oncology 》上值得一读。 癌症免疫中的 ...

为探究 STX12 缺乏的病理生理改变及致死机制，研究人员构建 Stx12 基因敲除小鼠和敲低斑马鱼模型开展研究。结果发现 STX12 缺失导致线粒体损伤、mtDNA 释放，激活 cGAS-STING 通路和炎症反应，这为揭示相关疾病机制提供了新视角。

Sting from a scorpion Onset of local pain and tingling after a scorpion is seen in the area The main symptoms are pain, tingling and numbness at the sting site About 85% cause only local symptoms at ...

Both Samuel and David, as youths, fulfill God's will; David and Goliath (1 Sam. 17:26,34-37,47); David gains the heart of all (18:16); Saul's jealousy of David (18:9-11). And David said to Saul, Let ...

Taohong siwu decoction (THSWD) has been shown to have a therapeutic effect on ischemic strokes (IS). However, it is not clear to us whether THSWD reduces deoxyribonucleic acid (DNA) damage after ...

Tourists in Cancun were left terrified as police clashed with alleged drug dealers in broad daylight at a resort, leaving one person dead. Guests in the pool area and at the nearby beach ...