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Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

为对比扎韦格潘（zavegepant）与口服 CGRP 受体拮抗剂治疗偏头痛的效果，研究发现前者起效快但长期优势不明显。 偏头痛，这种让人痛苦不堪的神经系统疾病，如同一个隐藏在暗处的 “小恶魔”，常常突然发起攻击。它以单侧或双侧搏动性头痛为典型特征 ...

CGRP-1, a downstream target of TRPM8, displayed the same trend across different groups ... MAPK is involved in various biological processes, including cell growth, differentiation, and apoptosis.

Mycobacterium tuberculosis prevents host-cell apoptosis, causing necrosis and fibrosis, leading to tissue damage. Singh et al. show that strategic targeting of apoptosis with Bcl-2 inhibitors may ...

Keratinocytes are the predominant block-building cells in the epidermis. Emerging evidence has elucidated the roles of keratinocytes in a wide range of pathophysiological processes including cutaneous ...

Excessive cell death has been associated with chronic inflammation as seen in patients with Crohn's disease and ulcerative colitis. While until recently apoptosis was discussed as being essential for ...

Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, characterized by rapid proliferation, extensive infiltration, and significant intratumoral heterogeneity. Despite ...