Imine reductases can catalyze reductive amination reactions to produce chiral amines, however, transformation of bulky amines has been challenging. Here, by using an increasing-molecule-volume ...

Supramolecular chirality sensor: A metal-containing porphyrin dimer was synthesized. This agent directly determines the absolute configuration of chiral amines and alcohols without any additional ...

Guangqing Xu: This work was not only valuable for synthetic organic chemistry but also made a breakthrough for pericyclic reaction theory. Kaidi Li: Over centuries, chemists have utilised chiral ...

A team of Japanese researchers has discovered a new technique to tweak molecular orientation that could dramatically improve energy transfer when absorbing light. While in its infancy, this ...

We have found that 2-lithiopyrrolidines, piperidines and other cyclic amines undergo dynamic resolution in the presence of a chiral ligand (L*), leading to highly enantioenriched 2-substituted cyclic ...

enabling alkyl amines with unactivated alkyl groups to be viewed as alkyl electrophiles. In a final area, we are developing new methods for enantioselective reactions of cationic intermediates using ...