It is likely that NHEJ and MMEJ contribute to some chromosomal rearrangements by joining non-homologous sequences. This might occur during repair of two-ended DSBs (such as endonuclease-induced ...
HMGA gene rearrangements, due to chromosomal translocations, are a feature of human benign tumours of mesenchymal origin. In most of the cases the breakpoint occurs in the third intron of the ...
Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
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