RAD54L2 deficiency phenocopies loss of BLM, including increases in sister chromatid exchanges and ultrafine anaphase bridges ... discovering statistically supported enrichments for DNA repair, DNA ...

We do not understand the nature of the factors that control the regional distribution of recombination along chromosomes, the mechanisms that control chromatid compaction and interference nor the ...

The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the biological sex, reproductive organs, and sexual characteristics that develop in a person.

A key target of the APC is securin, the destruction of which initiates chromosome segregation by unleashing the protease separase, which destroys sister-chromatid cohesion. The APC also ...

Women are born with two X chromosomes and inherit one from each parent. But in every cell of their body, just one X chromosome is needed—so the other is randomly inactivated. Some cells use only ...

Cephalopods may have the oldest sex chromosomes of any animal, according to a new discovery in the octopus genome. That's a big deal given that scientists didn't know until now if these oddball ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

This important study reports single-nucleus multiomics-based profiling of transcriptome and chromatin accessibility of mouse XX and XY primordial germ cells (PGCs). The main conclusions of this study, ...

OR, odds ratio; CI, confidence interval; snp, single-nucleotide polymorphism. Figure 6. Circos plot of co-expressed genes. The figure shows a circular chromosome diagram. The regions of different ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromosome segregation relies on kinetochores ...