One of cancer’s deadliest tricks is its ability to spread to other organs. An existing cardiac drug has now been found to reduce the risk of metastasis by dissolving circulating clusters of breast ...

Dr. Alan Tan spoke with CURE® about what patients with kidney cancer and providers who treat it may be able to learn from ...

Metastatic progression is the deadliest feature of cancer. Cancer cell growth, invasion, intravasation, circulation, arrest/adhesion and extravasation require specific mechanical properties to allow ...

Ultrasensitive detection of circulating tumor DNA can improve clinical outcomes in aggressive B-cell lymphomas by identifying measurable residual disease. Defining remission is challenging due to ...

In the next step, the researchers want to develop new molecules based on digoxin that are even better at dissolving the CTC clusters.

Read the paper: Digoxin for reduction of circulating tumor cell cluster size in metastatic breast cancer: a proof-of-concept trial CTCs can travel through the bloodstream either individually or as ...

Clinical Trial Registration ClinicalTrial.gov NCT01577511. Circulating tumour cells (CTCs) contain key prognostic markers for patients with metastatic colorectal cancer (CRC). CTCs are scarce among ...

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases. This is because the primary tumor continuously releases cancer cells into the blood.

Introduction: Circulating tumor cells (CTCs) have attracted significant interest as a biomarker for cancer diagnosis. In this study, we judiciously constructed a recombinant MUC1-dependent adenovirus ...