Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester have captured the first detailed ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer Center (MSK) set out to investigate G4s -- which have gained attention as ...

Cryo-electron microscopy of tau filaments from individuals with mutant V337M and R406W tau show the Alzheimer fold. The apical–basal polarity of epithelial cells depends on mutual antagonism ...

(In the benchmark dataset from the Electron Microscopy Data Bank, all the antibodies and Fabs are presumably known, as is the case for the monoclonal antibody CR3022). I am having difficulty ...

This approach aims to perform simultaneous antibody sequencing and epitope mapping using a combination of single particle cryo-electron microscopy (cryoEM) and bottom-up proteomics techniques based on ...

Cryo-electron microscopy of tau filaments from individuals with mutant V337M and R406W tau show the Alzheimer fold. The structure of chromatin bound by Polycomb repressive complex 1 (PRC1 ...

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and ...

Wolfgang Peti, PhD, professor of molecular biology and biophysics, shows us how cryo-EM works and how it can help speed up drug design and ultimately ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, ...