MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Deciphering the structures of proteins is critical to structural drug design. Cryo-electron microscopy (cryo-EM) now offers a radically different way to study the structure of large biomolecules ...

• Cryo-Autoloader for automated and contamination-free loading of cassettes, containing up to 12 Autogrids • Three-condenser lens system for automated, continuous parallel sample illumination tested ...

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer Center (MSK) set out to investigate G4s -- which have gained attention as ...

CU Boulder BioKEM facility added 200 kV Glacios TEM in the summer of 2023. Purchase and maintenance of the Glacios TEM is supported by generous contributions from Pfizer, Fiona & Marv Caruthers, and ...

The GW4 Facility for High-Resolution Electron Cryo-Microscopy provides access to cryo-microscopy to researchers in south west UK and beyond. In 2017, the GW4 Alliance opened a £2.3 million shared ...

Scientists at Forschungszentrum Jülich have now been able to gain fascinating new insights using cryo-electron microscopy. Their work is published in the journal Nature Structural & Molecular ...

The importance of this technology has also been recognized in Thailand, and the first cryo-electron microscope was introduced at Mahidol University last year. In this research, we aim to provide ...

By combining advanced electron microscopy with computational reconstruction algorithms, electron tomography provides unprecedented insights into the internal structure, composition, and properties of ...