急性肝损伤（ALI）死亡率高且缺乏有效靶向疗法。研究人员对 DHA 处理的 M1 巨噬细胞进行转录组和蛋白质组分析，发现 DHA 通过靶向 CYBA 和 CYBB 抑制 ROS 产生，减轻炎症。这为 ALI 治疗及炎症性疾病研究提供新方向。 急性肝损伤（Acute liver injury，ALI）是一种令人 ...

The authors used gain and loss of function techniques to provide convincing evidence showing that RUNX2 isoform silencing led to cell death via several mechanisms including apoptosis and ferroptosis ...

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. However, research on COX-2 regulation of ferroptosis ...

Conclusion: GFW supplementation attenuated BLM-evoked lung injury and pulmonary fibrosis partially through repressing EMT and mtROS-mediated ferroptosis in pulmonary epithelial cells. Adult male C57BL ...

Research has indicated that Citrus polymethoxyflavones (PMFs), a class of flavonoids found in Citrus, possess the potential to demonstrate anti-tumor efficacy. Ferroptosis a form of cell death that is ...

During Tuesday’s House Appropriations Committee hearing, Rep. Lois Frankel (D-FL) spoke of the benefits of continued funding for the President's Emergency Plan For AIDS Relief. Fuel your success ...