This cycle is divided into several phases, each of which is characterized by distinct cyclin proteins that act as key regulators for that phase. Before a cell can progress from one phase of the ...

The viral cyclin encoded by Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8) facilitates both cell-cycle progression and apoptotic cell death. Although they seem a paradoxical pair, the cell ...

An enzyme called cyclin-dependent kinase 2 (CDK2) regulates the cell cycle and may have the potential to drive therapeutic resistance to common breast cancer drugs—including a class of targeted ...