More recently evidence has been obtained showing an interplay between the nucleic acid metabolism of the nucleus and that of the cytoplasm 1. Studying the ultra-violet absorption spectra of the ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...

Automated and manual paraffin embedding (2 automated tissue processors, 1 manual embedding station, 1 paraffin oven). Cryo-sectioning, plastic sectioning, and vibratome sectioning for diverse sample ...

HistoSeg is an Encoder-Decoder DCNN which utilizes the novel Quick Attention Modules and Multi Loss function to generate segmentation masks from histopathological images with greater accuracy. This ...

“What I like about this technique is that you can see similar features as in conventional histology,” says Spies. “You can see structures such as collagen fibres, elastin fibres and cellular patterns, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Corneal diseases can cause severe visual ...

This important paper describes the regulatory pathway of rRNA synthesis by Meioc-Piwil1 in germ cell differentiation in zebrafish. Using the molecular genetic and cytological approaches, the authors ...

The FISH probe for circ_0098181 and the positive control of cytoplasm (18S probe) were synthesized by Ribobio Company (Guangzhou, China). In brief, the cells were fixed with 4% Paraformaldehyde (PFA) ...

Histopathological examination showed that numerous lymphocytes and a small number of histiocytes with abundant cytoplasm, vacuolated nuclei, and pronounced nucleoli were seen in the excised tissue ...

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...

Although RMS was once believed to arise from extraocular muscles, it is now accepted that orbital RMS develops from undifferentiated mesenchymal cells that have the capacity to differentiate into ...