A new study in Nature identifies a long-sought cytoplasmic 'sensor' that is responsible, at least in part, for interferon responses induced by double-stranded DNA. How do cells detect non-self ...

Over the past decade, there have been scattered reports of mammalian cells’ own DNA being found in the cytoplasm, mainly in the context of disease and aging. While it is not unusual to find DNA from ...

DNA is a single molecule, found free in the cytoplasm; additional DNA is found on one or more rings called plasmids. Eukaryotic cell DNA in a nucleus, plasmids are found in a few simple eukaryotic ...

DNA is normally contained in the nucleus and mitochondria, so when it shows up where it doesn’t belong—like outside the cell or floating in the cytoplasm—the cell immediately sounds the alarm. Cells ...