p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

As our bodies grow, cells proliferate to form tissues, and cells frequently have to be repaired or replaced throughout life..

Chromatin organization strengthens DNA for mechanically stressful processes like mitosis, helps protect DNA from damage and is important in the control of gene expression and DNA replication.

This article explores 6-base genome sequencing and how it is empowering researchers to expand their studies to include both ...

New research illustrates how a DNA repair protein suppresses senescent cells, reducing age-associated chronic inflammation.

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

New research uncovers new insights into preventing chronic inflammation caused by aging-related zombie-like cells. In humans ...

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma.

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.