Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective ...

The double ring, spool-like structure of RAD52 protects replicating DNA in dividing cells. A study led by the University of ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits.

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials ...

This study reveals how SV40 helicase unwinds DNA, highlighting ATP hydrolysis's role in translocation and offering insights into viral replication mechanisms.

Bioinformaticians from Heinrich Heine University Düsseldorf (HHU) and the university in Linköping (Sweden) have established ...

We show that saccharin mediates its antimicrobial activity via bulge-mediated cell lysis rather than through impacting DNA replication dynamics. We reveal that saccharin can inhibit a range of ...

DNA replication is one of the most well-orchestrated cellular processes that needs to proceed in a faithful and timely manner. However, this process is continuously challenged, leading to stalled ...

Are genes distributed randomly along the bacterial chromosome, as if scattered from a salt shaker? This opinion, which is ...