A photoswitchable, DNA structure-specific small-molecule probe, named G4switch, has been developed for the reversible targeting of DNA G-quadruplexes (G4s) in vitro and within cells. This ...

Institute of Resources & Environment, Henan Polytechnic University, Jiaozuo 454000, China ...

Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

This course offers an accessible introduction to the fundamental concepts of DNA and genetics, aiming to build a core understanding of how genes function and their role in shaping living organisms.

UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States Department of Medicine, University of California, San Francisco, ...

In a world where innovation, impact, and international reach are the cornerstones of modern leadership, Collins Nzekwe stands ...

Nes, BM ∙ Janszky, I ∙ Aspenes, ST ∙ et al.

The role and value of theory in improvement work in healthcare has been seriously underrecognised. We join others in proposing that more informed use of theory can strengthen improvement programmes ...

The Silver-Russell syndrome (SRS) is characterised by severe intrauterine growth retardation, with a preserved head circumference, leading to a lean body habitus and short stature. Facial dysmorphism ...

In a world that often celebrates overnight success, there exists a rarer breed: Entrepreneurs who build not just businesses but movements. As 2025 unfolds, a new wave of founders is emerging: ...