DNA can be further compressed through a twisting process called supercoiling (Figure 9). Most prokaryotes lack histones, but they do have supercoiled forms of their DNA held together by special ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

The Hopewell facility offers an integrated approach to manufacturing with in-house analytical testing, method development, ...

DNA gyrase operates like a tiny molecular machine, carefully twisting and stabilising bacterial DNA. This twisting, known as supercoiling, is similar to winding an elastic band: as it twists, it ...