DNA can be further compressed through a twisting process called supercoiling (Figure 9). Most prokaryotes lack histones, but they do have supercoiled forms of their DNA held together by special ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

DNA gyrase operates like a tiny molecular machine, carefully twisting and stabilising bacterial DNA. This twisting, known as supercoiling, is similar to winding an elastic band: as it twists, it ...

Mertz’s interests lay in the latter of these two projects. The scientific community knew little about SV40 or its supercoiled circular DNA at the time. Therefore, Mertz began a side project looking at ...

Hopewell-based team delivers on ProBio's promise of speed, quality, and reliability—offering a transparent, fixed-cost model and ≥85% supercoiled plasmid DNA in record time for clinical programs.