The enzyme dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of glucagon-like peptide-1 (GLP-1). Since GLP-1-based therapy is a promising novel treatment of type 2 diabetes, the strategy to ...

Alogliptin (NESINA), a dipeptidyl peptidase IV (DPP-4) inhibitor, was approved by the FDA on January 25, 2013 to improve blood sugar control in adults with type 2 diabetes. This drug had been ...

However, the existing computational methods are insufficient and inefficient to exploit enzyme structure. In this work, we introduce SEFP, a novel method leveraging enzyme point clouds for enzyme ...

A superposition of 539 equivalent Cα (lying within 3 Å) from monomers in the two complexes produced an r.m.s. distance of 1.4 Å ... the catalysis by malic enzymes. Structure refinement of ...

Some of these applications may be waiting for a discretionary permit to be approved, and these will not be expired, DPP said. On the commercial side, there are 3,267 commercial permit applications ...

Dipeptidyl peptidase-4 (DPP-4) is an enzyme that destroys hormones called ... This type of weight loss surgery changes the ...

Flavonoids are categorized into several subclasses based on their chemical structure ... flavonoids inhibit dipeptidyl peptidase-4 (DPP-4), the enzyme responsible for incretin degradation ...

The leader of a key opposition party in Japan said the central bank may have to reverse course on policy, not only putting aside any notions of hiking interest rates but also being prepared to ...

The Witcher 4 is going to be a single-player open-world RPG. Developer CD Projekt RED believes it'll be the "most immersive and ambitious open-world Witcher game to date." ...