Bernd Kasper, MD, PhD, provides an overview of the phase 3 DeFi trial of nirogacestat for the treatment of patients with progressing desmoid tumors. Bernd Kasper, MD, PhD, professor, ...

Bernd Kasper, MD, PhD, discusses the key efficacy results from the updated analysis of the phase 3 DeFi trial of nirogacestat in desmoid tumors. Bernd Kasper, MD, PhD, professor, Universitätsmedizin ...

Researchers from Tel Aviv University utilized CRISPR to cut a single gene from cancer cells of head and neck tumors—and successfully eliminated 50% of the tumors in model animals. This study was ...

In normal adult tissues, SOX2 is mostly quiet. But in many cancers—including head and neck tumors—it’s turned on way too much. This gives cancer cells stem-like powers, helping them grow ...

Tel Aviv University researchers used CRISPR to cut the SOX2 gene from head and neck cancer cells, eliminating 50% of tumors in mice. The study, published in Advanced Science, highlights CRISPR’s ...

After treatment for a surgery for a head and neck cancer, it is important to contact your specialist doctor or nurse if you notice any changes in the treated area. They can tell you if the symptoms ...

SpringWorks Therapeutics portfolio features Ogsiveo for desmoid tumors and Gomekli for NF1‑plexiform neurofibromas. In fact, Ogsiveo’s revenues alone reached $172 million in 2024, supported by ...

The results of the DeFi trial of nirogacestat in 142 adults with progressing desmoid tumours showed a ... DeFi investigator Bernd Kasper of Mannheim Cancer Centre in Germany (pictured above ...

A lump in your neck may be caused by an infection or an immune reaction to the infection. It may involve an abnormal growth of tissues or changes in cells that lead to cancer. Some of these causes can ...