Our data showed an atypical expression profile of dopamine receptor D2 (DRD2) in various cell lines of SCLC belonging to NE, non-neuroendocrine, brain metastatic (BrM), and chemotherapy-resistant ...

In a placebo-controlled, double-blind, balanced crossover experiment, we show that the dopamine D2-like receptor agonist pramipexole given during sleep wipes out reward contingencies. Before sleep, 16 ...

At the same time it also avoids stimulating similar receptors, such as the dopamine D2 receptor, that can lead to unwanted side effects. This type of selective dual targeting is a major challenge ...

Following acute multiple trauma, hypothalamic stimulation of the sympathetic nervous system and adrenal glands causes an increase in circulating corticoids and catecholamines, or a stress response ...