Scale-up is a common problem encountered in all forms of development across industries, and oral solid dose manufacturing ...

Many diseases remain untreatable, not because they are rare or unknown, but because their biological targets are so difficult to drug. Drug discovery, however, is fraught with challenges ...

Interested in finding a better way to develop drugs to treat amyotrophic lateral sclerosis (ALS), Northeastern researcher ...

Partnership brings into sharper focus need to integrate target engagement and target engagement and physiopathology candidate profiling solutions to optimize drug development process and increase ...

One of the most exciting parts of the study involved testing a drug called seclidemstat. This drug is already in early clinical trials for another cancer called sarcoma. The team found that ...

8 April 2025 | By Drug Target Review Researchers from Mass General Brigham have developed a hydrogel to improve drug delivery for post-traumatic osteoarthritis (PTOA), which ensures sustained ...

While much of the conversation around the Trump administration’s potential pharmaceutical import tariffs has leaned heavily ...

A team of scientists from the University of Birmingham has discovered a powerful new treatment for psoriasis. The treatment uses a tripeptide that has shown steroid-level effectiveness in reducing ...

These results suggest that measuring the expression level of SHP2 could be vital when choosing a drug for the target. Figure 1. Western blot of four cell lines tested against 15 compounds ...

Drug-target affinity prediction (DTA) is an important task in the early stages of drug discovery. Traditional biological approaches take a long time and use a lot of resources because of the large ...

Which modality would be the most effective way to drug a target of interest? Experts say there’s no field-wide framework for making that decision. It involves weighing what you know about a drug ...

Essential antioxidants and immune-boosting elements abound in Tonic Greens' 6-in-1 mix. It is a nutritional supplement ...