In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Given the recent increases in the incidence of diabetes, obesity and hyperlipidemia, there is a pressing need for low cost therapeutics that can economically and effectively slow the progression of ...

HIF-1α exerts both detrimental and beneficial actions in atherosclerosis. While there is evidence that HIF-1α could be pro-atherogenic within the atheromatous plaque, experimental models of ...

Information about how we partner with researchers from across the globe to bring their most significant discoveries to the widest possible audience.

The potential of efficiency to support decarbonization is underestimated and overlooked relative to more expensive and intensive actions. Implementing resource and energy efficiency strategies in ...

and dyslipidemia. Several studies have shown that individuals with NAFLD are more likely to have atherosclerosis and a heightened risk of cardiovascular disease than individuals without NAFLD.

This common scenario presents a diagnostic conundrum whereby angina occurs but there is no obstructive CAD (ischaemia and no obstructive coronary artery disease—INOCA). We review new insights into the ...

Jan. 30, 2025 — People who regularly floss their teeth (one or more times per week) may lower their risk of stroke caused by a blood clot traveling from the heart and a stroke associated with an ...

From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...