Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

Toxicology Centre, University of Saskatchewan, Saskatoon, SK S7N 0H5, Canada School of Environment and Sustainability, University of Saskatchewan, Saskatoon, SK S7N 5C8, Canada Global Institute for ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

A pinched nerve occurs when there is pressure or force on an area of a nerve, causing it to send pain signals to the brain. Most cases are mild, and a person can often treat them at home. In this ...

"Delta receptors are located throughout the body on pathways and neurons that transmit pain signals to the brain," said Jay McLaughlin, Ph.D., a professor of pharmacodynamics in the UF College of ...

Ecotoxicology seeks to understand how toxic chemicals (toxicants) affect the structure and function of natural ecological systems (populations, communities and ecosystems). The eriss ecotoxicology ...

Sulfoxaflor, a systemic insecticide, causes impacts on reproductive behaviors and male fertility in the red mason bee species ...

Introduction: The Constitutive Androstane Receptor (CAR) (NR1I3), a pivotal member of the xenosensor family, plays a key role in the hepatic detoxification of xenobiotic and endobiotic chemicals ...

To date, almost 1,000 different active pharmaceutical substances have been detected in environments worldwide. Particularly ...

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China University of Chinese Academy of ...