Department of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China ...

2022). Nevertheless, the involvement of HSPA5-mediated ferroptosis in kidney fibrosis has not been documented, and the mechanism behind it is still unknown. Endoplasmic reticulum stress (ERS) was ...

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting ...

Scientists have uncovered more than 20 genes whose mutations cause familial forms of Parkinson's disease. One of these genes ...

Correspondence to Dr Sang Geon Kim, College of Pharmacy, Seoul National University, Sillim-dong, Kwanak-gu, Seoul 151-742, South Korea; sgk{at}snu.ac.kr Objective Endoplasmic reticulum (ER) stress is ...

Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati 45267, Ohio, United States The Materials Science and Engineering Program, Department of Mechanical and Materials ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes ...

Scientists apply principles of math and physics to unravel the mystery of how the endoplasmic reticulum, an organelle vital ...

Researchers from Aarhus University and Synuca Therapeutics recently presented a novel drug-like small-molecule inhibitor of sarco/endoplasmic reticulum calcium ATPase (SERCA), SYN-4569, with superior ...