Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short. Among other things, they regulate inflammatory reactions and influence ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9 – DPP8/9 for short. Among other things, they ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation. For organs to develop, grow and regenerate, cells must proliferate.

In a breakthrough with promising real-world applications, a team of Rutgers biophysicists, bioengineers, and plant biologists has captured the first live images. In a groundbreaking study, researchers ...

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...

But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge. "This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

The question was whether it would work in cells. Unfortunately, one of the two enzymes turns out to be mildly toxic to E. coli, slowing its growth. So, the researchers evolved a strain of E.