Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short. Among other things, they regulate inflammatory reactions and influence ...

Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

In a breakthrough with promising real-world applications, a team of Rutgers biophysicists, bioengineers, and plant biologists has captured the first live images. In a groundbreaking study, researchers ...

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation. For organs to develop, grow and regenerate, cells must proliferate.

But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge. "This work addresses a long-standing mystery surrounding an enzyme critical for regulating the cell cycle ...

A study identifies senolytic compounds that can inhibit specific brain enzymes associated with Alzheimer’s disease (AD) while ...

A team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific ...

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...

After this synthesis had been completed, preparation of Nα-benzoyl-dl-arginme-β-naphthylamide hydrochloride via the carbodiimide procedure was reported (cf. ref. 2). Gomori, G., J. Histochem ...

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge. New CU Boulder research, published in ...

Eddy, A. A., and Williamson, D. H., Nature, 179, 1252 (1957).

The gene encoding an enzyme from a firefly, discovered at the Sorocaba campus of the Federal University of São Carlos (UFSCar ...