A research team led by Dr. Martin Mollenhauer from the Heart Center at University Hospital Cologne has investigated the link ...

A metabolic vulnerability of pancreatic ductal adenocarcinoma (PDAC) could be used to address this type of cancer that often resists treatments. Scientists at the University of Michigan have ...

Hypotension is not a specific side effect with ACE inhibitors; rather, it is a broadening of the physiologic action of these drugs that occurs most commonly when a patient becomes volume contracted.

Pancreatic cancer is a leading cause of cancer-related death, with a five-year survival rate of 13%. The high mortality is ...

In addition, the clopidogrel acyl-glucuronide metabolite is a known strong time-dependent inhibitor of CYP2C8 leading to marked clinical DDIs with the substrates of this enzyme. Patients on ...

In using nojirimycin derivatives as glycosidase inhibitors, a large dose of the compounds is required to secure an effective endoplasmic reticulum lumenal concentration to eliminate the enzyme ...

Discover why BTK inhibitors have attracted interest for treating multiple sclerosis, as a few late-stage candidates close in ...

Study Objectives: To assess the clinical relevance of angiotensin-converting enzyme inhibitors (ACEI) and 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors (statins) in the context of ...

While sprinkling cinnamon on food is likely safe, concentrated supplements might pose risks, especially for people taking ...

Lorundrostat, a selective aldosterone synthase inhibitor, significantly reduced systolic blood pressure in patients with ...