Boosting MTMR7 production reversed signs of pulmonary arterial hypertension in a mouse model of PAH and may serve as a ...

Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity ...

"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...

p-extracellular signal-related kinase (ERK), t-ERK, p-p38, t-p38, p-c-Jun N-terminal kinases (JNK), t-JNK, p-Signal transducer and activator of transcription 3 (stat3), t-stat3 (Cell Signalling ...

This was accompanied by an impairment of mitochondrial function with reduced expression of carnitine palmitoyltransferase I and an induction of acyl-coenzyme A oxidase-1 (ACOX1), oxidative stress and ...

高浓度的谷氨酰胺和丙氨酸能够激活 mTOR-STAT3 和 ERK-CREB 通路，进而上调 VGF 和 Gcg 的表达。 研究结论与意义 这项研究首次在单细胞水平揭示了 GCGR 阻断后 α 细胞胰高血糖素分泌增加的现象，明确了 VGF 在其中的关键作用，并且找到了导致 VGF 上调的 “元凶 ...

当某知名企业家公开抗癌经历引发社会关注时，全球医学界正悄然进行着一场静默革命。最新数据显示，全球每年新增肿瘤患者超2000万例，传统疗法有效率徘徊在40%-60%之间。在这场关乎人类健康的持久战中，科学家意外发现：肿瘤微环境中密布的神经纤维不仅是疼痛传导器，更可能是癌症进展的"帮凶"。这一发现颠覆了传统认知，将神经系统推向了抗癌研究的最前沿。

You can create a release to package software, along with release notes and links to binary files, for other people to use. Learn more about releases in our docs.

Docs and examples to StPageFlip: https://nodlik.github.io/StPageFlip/ Docs (generated by TypeDoc): https://nodlik.github.io/StPageFlip/docs/index.html ...