According to the National Cancer Institute, roughly 15% of breast cancer cases are hormone-receptor negative, in which breast cancer cells do not contain hormone (estrogen or progesterone) receptors.

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Selective estrogen receptor modulators (SERMs) and selective estrogen receptor downregulators (SERDs) are types of antiestrogen therapy for breast cancer. These medicines block estrogen ...

The androgen receptor (AR) is a member of the nuclear hormone receptor superfamily and a key driver of prostate tumor growth ... such as AR amplification or point mutations in the ligand binding ...

Estrogen Receptor Subtypes & Bioidentical Estrogens Estrogen-receptor subtypes may influence how various estrogens act in different tissues. Estradiol binds equally to estrogen receptors α and ß ...

State Key Laboratory of Pollution Control and Resource Reuse, Institute for the Environment and Health, Nanjing University, Nanjing, Jiangsu 210023, PR China ...

Estrogen receptor-positive (ER+) breast cancer, which makes up around 70% of all breast cancer cases, often becomes resistant to current hormone therapies. Now, researchers have designed and ...

Treatment may include medication, surgery, or radiation therapy. Phytoestrogens are plant compounds that bind to estrogen receptors in the body’s cells. They can raise or lower estrogen levels, though ...

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First-in-human trial of ETX–636 to begin in Q2 2025 in patients with tumors harboring an activating PI3Kα mutation, including breast cancer ...