为探究膜裂变的机制，研究人员开展了关于网格蛋白（Clathrin）是否为膜裂变蛋白的研究。结果发现，膜窖包被蛋白尤其是网格蛋白，可能通过在 Ω 形轮廓底部或头部聚合，引发颈部收缩来介导裂变，这对理解多种内吞模式意义重大。 膜裂变被认为涉及形成螺旋 ...

Exosomes, nano-sized extracellular vesicles secreted by all cells, are a fundamental part of the human body’s internal communication machinery, safely and efficiently transporting proteins and ...

Exosomes have been associated with disease development in cancer, neurodegeneration and inflammatory disorders. ExosomeDx harnesses biological information from exosomes for biomarker discovery and ...

After decapping, 5’ to 3’ RNA degradation is accomplished by Xrn1, a 5’ to 3’ exoribonuclease. In the 3’ to 5’ pathway, RNA degradation is catalyzed by a multi-subunit 3’ to 5’ exoribonuclease complex ...

Secreted vesicles known as exosomes were first discovered nearly 30 years ago. But, considered little more than garbage cans whose job was to discard unwanted cellular components, these small vesicles ...

But it is dermatology’s newest hot topic, exosome therapy, that reminds her of the starfish she grew up watching, with their magically regenerative bodies. Exosomes are nano-size vesicles (sort ...

Researchers at The Ottawa Hospital and the University of Ottawa have discovered an 18-digit code that allows proteins to attach themselves to exosomes—tiny pinched-off pieces of cells that ...

Get Instant Summarized Text (Gist) A bifunctional exosome-based drug delivery system was developed to target metabolic dysfunction-associated steatohepatitis (MASH). By engineering exosomes to ...

Rich in micro-RNA and other short-fragmented RNA sequences essential for cell-to-cell communication, exosomes have emerged as pivotal components in pathology and disease progression. Image Credit ...