Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Protein Kinase A (PKA) is regulated spatially ...

为探究高尔基体组装及细胞迁移的调控机制，研究人员开展了关于 Rab32 作用的研究。发现 Rab32 通过 PKA 介导 Optineurin（OPTN）磷酸化调控高尔基体动力学，且该过程影响肿瘤细胞侵袭，为相关疾病研究提供新思路。 在细胞迁移过程中，高尔基体的组装和动态变化 ...

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在神经科学领域，蛋白激酶 A（PKA）和细胞外信号调节激酶（ERK）对学习和记忆至关重要，但它们的信号交互机制不明。研究人员以果蝇为模型展开研究，发现 PKA 限制 Kenyon 细胞中 ERK 信号传导。这为理解神经信号通路提供依据，对相关疾病研究意义重大。

The 2024-25 Premier League table is tight for European qualification as another season of chaos approaches its climax. MORE-Premier League 2024-25 schedule, how to watch live It seemed clear that ...

烯醇结构的羟基氧上一对P电子和碳碳双键中的π键形成P-π共轭体系，使电荷在一定程度上偏向碳端，增加了羟基氧氢键的极性，使氢更容易离去（pKa：10.94），不好理解的话可以参考苯酚结构。氢离子离去后形成烯醇负离子是一个三原子四电子的共轭体系 ...

Joe Rondone / The Republic / USA TODAY NETWORK / USA TODAY NETWORK The report adds, "Jerry Jones has had extensive talks with Parsons about his contract," but notes "no serious talks" have been ...

BENSALEM, PA – Dr. Neil K. Anand, a 48-year-old Pennsylvania physician, faces a statutory maximum penalty up to 130 years in federal prison after being convicted by a jury for his leading role ...