NETs formation in extracellular matrix was visualised by laser scanning confocal microscopy. Succinate receptor (SUCNR1) antagonist was used to investigate its effect on the generation of NETs.

G protein-coupled receptors (GPCRs) are involved in many diseases, yet raising therapeutic antibodies against them is notoriously difficult because the transmembrane receptors contain only short ...

bacterial receptors, shown in mesh representation over the entire length of the protein. Only three subunits of the extracellular domain and transmembrane domain are shown (in grey) for clarity.

TNBC is a heterogeneous disease characterized by lack of expression of three receptors: estrogen (ER), progesterone (PR), and human epidermal growth factor receptor 2 (HER2), resulting conventional ...

G protein-coupled receptors (GPCRs ... nucleotide-binding proteins), which are important for transmitting the extracellular, ligand signal to the cell interior. G protein-coupled receptors ...

Our brain requires a constant supply of energy. A disrupted energy supply, as, for instance, caused by a stroke, can have ...

Aurobindo Pharma's biosimilar for breast cancer recommended for EU approval, demonstrating similarity to Herceptin.

More information: Yen‐Ting Lu et al, Small Extracellular Vesicles Engineered Using Click Chemistry to Express Chimeric Antigen Receptors Show Enhanced Efficacy in Acute Liver Failure ...

A new study shows that when energy is depleted—such as during a stroke—neurons begin releasing glutamate in abnormal, self-amplifying bursts that can damage nerve cells.

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...