The full-length IgG format also enables further modification of the Fc region for enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) or to prevent binding to Fc-γ receptors on immune ...
Researchers from Abl Bio Inc. have published preclinical data for ABL-112, an Fc-competent bispecific antibody (BsAb) targeting TIGIT and 4-1BB (TIGIT x 4-1BB), being developed for the treatment of ...
On March 13, 2025, the US Court of Appeals for the Federal Circuit (Federal Circuit) issued a decision titled In Re: Xencor, Inc. (the ...
Anti-LAG-3 MAb (Human IgG1) captured on CM5 chip via Anti-Human IgG Fc antibodies surface, can bind Human LAG-3, His Tag (Cat. No. LA3-H5222) with an affinity constant of 4.57 nM as determined in ...
Binds human Fc-fusion proteins and human IgGs. Suggested for kinetic screening, epitope binning, off-rate antibody ranking, and quick quantitation screening. High-performance nanobody-based ...
Otsuka’s Taiho Pharmaceutical is paying $400 million upfront to acquire Switzerland’s Araris Biotech and its antibody-drug conjugate (ADC) linker platform.
Adagene Inc. (“Adagene”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based ...
Lundbeck has gained orphan drug designation (ODD) from Japan’s Ministry of Health, Labor and Welfare (MHLW) for amlenetug to ...
Complementing its antibody offerings, BosterBio provides a range of ELISA kits designed for quantitative detection of proteins, cytokines, and other biomarkers. These kits are widely used in drug ...