Cysts, fibrosis, and tubular degeneration form the typical triad of pathologies leading to the gradual decline in kidney ...

Major discrepancies are seen with the use of noninvasive tests compared with liver biopsy in a posttransplant setting.

Good morning! Citigroup in the middle of funding freeze fallout, Ursula von der Leyen offers Trump a “zero-for-zero” tariffs ...

More information: Margaret A.T. Freeberg et al, Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation, The American Journal of Pathology (2025). DOI ...

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window States screen for cystic fibrosis (CF) but with significant variation among their screening algorithms. The Cystic ...

Objective Bone morphogenetic protein 6 (BMP6) has been identified as crucial regulator of iron homeostasis. However, its further role in liver pathology including non-alcoholic fatty liver disease ...

The study, “Piezo2 Is a Key Mechanoreceptor in Lung Fibrosis that Drives Myofibroblast Differentiation,” was published in The American Journal of Pathology. In IPF, scar tissue buildup in the lungs ...

Hepatic fibrosis is a reversible wound healing response characterized by accumulation of extracellular matrix (ECM), or "scar," that follows chronic but not self-limited liver disease. The ECM ...

Protein clustering mechanism on the cell membrane presents a new therapeutic target for cystic fibrosis. A new study from The Hospital for Sick Children (SickKids) reveals the process underlying ...

Piezo2 is increased in idiopathic pulmonary fibrosis (IPF). Immunohistochemistry of nonfibrotic (left) and IPF (right) lung tissue demonstrating that Piezo2 (brown staining) is strongly present in ...

A therapy using a patient's own proximal basal stem cells shows promise to treat idiopathic pulmonary fibrosis.