The pathological mechanisms of AS involve endothelial cell (EC) injury and dysfunction, vascular smooth muscle cell (VSMC) migration and proliferation, foam cell formation, inflammatory cell ...

During atherogenesis, macrophages turn into foam cells by engulfing lipids present within the atheroma plaques. The shift of foam cells toward proinflammatory or anti-inflammatory phenotypes, a ...

Additionally, the bioactive PUr SMP foams promoted cell attachment, spreading, and proliferation on foam pores, which could facilitate tissue migration into the scaffold and promote wound repair.

Introduction: Lipid accumulation and foam cell formation are significant features that expedite the progression of atherosclerosis (AS). Abnormal autophagy is a key factor in the development of AS.

Moreover, Cryptococcus- and Mycobacterium-infected macrophages accumulated triglycerides in different ways. Collectively, the data show that the molecular events underlying foam cell formation are ...

Our results demonstrate an important role for filopodia and the regulating protein—espin in confined cell migration and shed new light on cytoskeletal mechanisms underlying metastasis. Espin induces ...

Journalists are invited to join Johns Hopkins University experts for this monthly virtual briefing series exploring aspects of artificial intelligence ...