Fibroblasts are the most common cell type in connective tissue. They can be compared to 'nature's stitches', holding together ...

On binding to ECM molecules, integrins are thought to undergo a conformational change, which allows the intracellular domain of their β-subunit to interact with focal-adhesion proteins ...

A mouse fibroblast cell imaged on a metasurface ... and confined emission from light-emitting paxillin protein at focal adhesions near the membrane. Researchers at Kyushu University have shown ...

Even more fascinating is the intricate relationship between lysosomal exocytosis and focal adhesions, structures critical for cell anchoring and communication. By decoding how focal adhesions ...