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TAx9 技术:突破 Cre-loxP 系统构建难题,加速基因编辑研究进程
此外,TAx9 技术具有广泛的应用前景,原则上不仅可用于标准和诱导型 Cre-loxP 系统,还可应用于多种条件基因修饰工具,如 Flp-frt 和 Dre-rox 等 。它能够与 RNA 干扰或 CRISPR-Cas9 基因组编辑工具相结合,实现对基因表达的时空特异性调控,包括基因过表达、基因敲低 ...
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