Over the past fifteen years, great strides have been made to understand how heterotrimeric G proteins control their ... allosteric machines with multiple signaling outputs. You have full access ...

While interindividual variations in concentration and function of coagulation cascade proteins are established risk factors for venous thromboembolism (VTE), their associations with arterial ischemic ...

The complement system plays crucial roles in innate immunity and inflammatory responses. The anaphylatoxin C3a mediates pro-inflammatory and chemotactic functions through the G protein-coupled ...

It provides 53 g of protein per serving and a hearty dose of complex carbs and healthy fats, so it’s a good option for people who are trying to gain weight or may have difficulty meeting their ...

In vertebrates, the majority of the cells in the lens are fiber cells. Focusing on Grb2 – a protein that is essential for activating Ras-MAPK signaling – Wang et al. showed that deleting the gene for ...

Our study demonstrates that SELENOT in mouse dopaminergic neurons maintains proper dopamine signaling in the midbrain against the development of ADHD-like behaviors. The ER membrane protein SELENOT ...

Cysteinyl leukotrienes (CysLTs) are potent bronchoconstrictors, playing pivotal roles in inflammatory diseases. These lipid mediators exert their ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

A study by Kindai University researchers shows that neurons adapt their migration strategies based on environmental ...