为探究心肌细胞增殖调控机制及治疗心肌梗死，研究发现 circALPK2/miR-9/GSK3B 轴可促进心肌再生 ... circALPK2 作为一种负调控因子，通过海绵机制抑制 miR-9，进而上调 GSK3β 的表达，抑制 WNT 信号通路，最终抑制心肌细胞增殖和心脏修复。敲低 circALPK2 则可打破这种 ...

The study focused on variants in the GSK3B gene, which had not been well-understood previously. Researchers found that individuals with GSK3B variants shared common symptoms, including ...

Forbes contributors publish independent expert analyses and insights. Asif Burhan is a freelance journalist who covers women's soccer.

2023). Table 1. Molecular docking results between MA and core targets. Overall, the molecular docking analysis indicated strong binding affinities between MA and several key proteins associated with ...

Studies have shown that the anti-disease effect of catalpol in osteoporosis (OP) is mainly achieved through various pathways such as Wnt/β-catenin signaling pathways to promote osteogenic ...

There are currently 35 places between Ireland (25) and Türkiye (60) in the FIFA Women’s World Rankings. - Türkiye will become the 55th different team that Ireland will have faced for the first time at ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...