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该研究首次阐明Miro1 N端GTPase结构域在神经分化中的核心调控作用,为预防产前应激导致的神经精神疾病提供新靶点。 在生命早期,母体经历的应激事件可能通过胎盘屏障影响胎儿神经发育,这种"编程效应"往往导致子代成年后出现认知障碍和情绪异常。尽管已知 ...
A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...
The epithelial–mesenchymal transition is the process by which polarised epithelial cells that are connected via adhesion lose their characteristics and acquire migratory and invasive properties ...
Synaptic plasticity is the biological process by which specific patterns of synaptic activity result in changes in synaptic strength and is thought to contribute to learning and memory. Both pre ...
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