Xiong has identified a key regulator for GTPase function called CalDAG-GEFI (CDGI) to control the switch of binding GTP or GDP of LRRK2 GTPase. Most other research has focused on understanding and ...

In 2000, Zhang & Clarke used a strategy with artificial beads to prove the direct function of Ran GTPase in NE assembly. The artificial beads are made of solid sepharose, and thus have the ...