Clarke, PhD, professor at The Hormel Institute, University of Minnesota, is the author of a paper appearing in the scientific journal iScience titled "Aromatics from fossil fuels and breast cancer." ...

At meeting on human embryo editing, CRISPR pioneer says science is a long way from knowing if germline DNA can be safely ...

A new multi-generational study suggests that the effects of violence can remain in your genes—and be passed down to future ...

During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner.

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.

With this approach, we have determined that unusual DNA structures (i.e., palindromes, as well as double-strand breaks) stimulate germline recombination events to a high degree (Akgün et al. Mol Cell ...

Germline stem cells from the postnatal testis can convert into ES-like, multipotent germline stem cells without any genetic treatment. We will examine 1) the differences between SSCs and ES cells, 2) ...

contains two different cell types- germ cells that will eventually become sperm and somatic cells that support the germline within the niche and as germ cell differentiate. Our lab has identified ...

These strategies include the reassembly of naturally occurring genes encoding the heavy- and light-chain domains from either immune 1,2 or nonimmune B-cell sources 3, or introduction of synthetic ...