The widely accepted concept of the neurovascular unit suggests that proper brain function relies on dynamic communication and homeostatic signaling among neurons, glial cells, and vascular compartment ...

Traumatic brain injury, stroke, and degenerative diseases elicit complex pathogenic cascades involving glial cells such as astrocytes, microglia, and ...

In a recently published review, researchers led by Prof. Wu Qingfeng at the Institute of Genetics and Developmental Biology ...

Taking advantage of several genetic reporter and fate tracing tools, the authors provide solid evidence for different forms of glial plasticity, that are increased upon injury. The significance of the ...

Despite substantial efforts, the molecular mechanisms by which 25-OHC affects glial cells in diseases like amyotrophic lateral sclerosis (ALS) remain unclear. Against this backdrop, a research ...

and give rise to new neurons and supporting cells called glial cells. Activation of neural stem cells or their transplantation into areas of central nervous system injury can lead to regeneration ...

Oligodendrocytes are a type of large glial cell found in the central nervous system. Oligodendrocytes produce the myelin sheath insulating neuronal axons (analogous to Schwann cells in the ...

AskBio's approach meanwhile will involve using an adeno-associated virus (AAV) vector to deliver a gene for human glial cell line-derived neurotrophic factor (GDNF) into the neurons in the putamen.

For the first time, researchers have suggested a breakthrough drug that could fully replicate the benefits of physical stroke ...