However, the exact pathogenesis of PD remains unclear, with ferroptosis emerging as one of the key factors driven by iron accumulation and lipid peroxidation. Glial cells, including microglia, ...

Patients and methods: Surgical specimens from 26 severely constipated patients were assessed by conventional and immunohistochemical methods. Specific staining for enteric neurones, glial cells, ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

New research reveals the cellular secrets of aging, with cutting-edge single-cell data mapping how neurons, glial cells, and immune systems reshape the aging brain. Study: Brain-wide cell-type ...

Ischemic cascade. The relay of extracellular and intracellular processes leading to pathogenic states and eventually to cell death. Glutamate uptake via EAATs serves as a major mechanism for ...

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

Like previous studies, the initial results showed a decrease in the activity of genes associated with neuronal circuits. These decreases were seen in neurons, the primary circuitry cells, as well as ...

Detailed mapping of 1.2 million brain cells has revealed that not all cell types age in the same way and that some – found in a specific ‘hot spot’ – are more sensitive to the aging process.

Traditionally, scientists organized brain cells into two major types: neurons and glial cells. Neurons carry electrochemical signals, a bit like the copper wiring in a building. Glial cells ...

Glia are a non-neuronal category of cells that do not transmit electrical signals but still form an important part of the nervous system. Glial cells provide structural and other kinds of support ...

Emerging evidence highlights the dual role of oligodendrocytes in Alzheimer’s disease, both providing protective mechanisms against the pathology and contributing to its progression. AstroNet, a ...