So when Amanda Andersson-Rolf, a postdoctoral researcher in Hans Clevers’s group at the Hubrecht Institute, set out to build a better pancreatic organoid, she decided to include all three main cell ...

The organoid's ... Molecular Zip Code Draws Killer ... The cells are hybrids, part neuron and part glia, and are present in both glioma, a type of brain tumor, ... Sep. 3, 2024 — Researchers ...

Malignant gliomas and medulloblastomas — the most common brain tumours affecting adults and children, respectively — remain responsible for a disproportionate level of morbidity and mortality ...

This mechanical feedback is a key driver of crypt formation. "As the organoid's lumen volume decreases, the tissue bends, and crypts emerge," Liberali says. To test their model, the researchers ...

Organoid technology has lately risen to prominence as a critical tool for both basic and biomedical research. Embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and primary ...