Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

disorders in the metabolism of complex molecules (peroxisomal diseases, lysosomal diseases, congenital disorders of glycosylation and inborn errors of cholesterol synthesis, and other IEM affecting ...

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We led a study to find out how genes have such a significant influence on why humans (and dogs) become overweight. It was ...

Empagliflozin patent expiration in India leads to affordable treatment for diabetes, heart failure, and kidney disease.

Such crossover is not astonishing; both dogs and humans evolved to deal with cycles of food glut and famine ... the brain by ...

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Inositol supplements show significant benefits for hormonal disorders, insulin sensitivity, and fertility issues, offering a ...

Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...