Glutamine is deaminated to form glutamate, which is processed to produce a-KG for use in the TCA cycle. HIF-1 is a heterodimeric protein that could alter various genes coded for enzymes involved in ...

There is increasing evidence that the metabolic status of T cells and macrophages is associated with severe phenotypes of chronic inflammation, including allergic inflammation. Metabolic changes in ...

More information: Joeri Bordes et al, Sex-specific fear acquisition following early life stress is linked to amygdala and hippocampal purine and glutamate metabolism, Communications Biology (2024).

Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters, may help alleviate symptoms of fibromyalgia (FMS) and chronic fatigue syndrome (ME/CFS).

We see the seven stones of the Molecular Systems Biology cover as a visual allegory for Aristotle's visionary thought: The whole is greater than the sum of its parts.

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Energy metabolism is the process of generating energy (ATP) from nutrients. Metabolism comprises a series of interconnected pathways that can function in the presence or absence of oxygen.

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A brand new candidate for weight-loss treatment is on the table, with scientists uncovering for the first time how a hormone ...