This work by the Meng lab investigates the role of the proteins MARK2 and CAMSAP2 in the Golgi reorientation during cell polarisation and migration. They identified that both proteins interact ...

IT has become customary in studies of the nerve cell by electron microscopy to apply the term ‘Golgi apparatus’ to appearances suggesting membranes, granules, or vacuoles 1. In size ...

BACKGROUND: Morbidity and mortality of heart failure with preserved ejection fraction (HFpEF) is increased in metabolic disorders. However, options for preventing and treating these prevalent outcomes ...

Image Pro Plus 6.0 software was used for image quantification. The investigators were blinded to different groups when performing histology staining and analyzing the data. For in vitro and in vivo ...

This important study shows that a very slow (infraslow) oscillation occurs in voltage recordings from the dentate gyrus of the adult mouse. The authors suggest that it is related to sleep stage and ...

Correspondence to Professor Masaaki Murakami, Division of Molecular Psychoimmunology, Institute for Genetic Medicine, Graduate School of Medicine, Hokkaido University, Sapporo, Japan; ...

Department of Pediatrics, Jinniu District Maternal and Child Health Hospital, Chengdu, China Background: The escalating global cancer burden, projected to reach 35 million new cases by 2050, ...

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline and neuronal degeneration. Emerging evidence implicates necroptosis in AD pathogenesis, driven by the ...

Belgium We thank Rose-Marie Goebbels for her assistance with histology staining. A.B. is a research associate from the Belgian FRS-FNRS (Fonds de la Recherche Scientifique) and a WEL Research ...

为了揭开这些谜团，美国国立卫生研究院（NIH）等机构的研究人员开展了一项重要研究，相关成果发表在《Journal of Molecular Histology》杂志上 ... 基于 E 和 3a 蛋白在 ER、ER-Golgi 中间区（ERGIC）和高尔基体的定位，研究人员检测了感染或转染后细胞中 ER 应激和未 ...

Axons of dopaminergic neurons projecting from substantia nigra to striatum are severely affected in the early stage of Parkinson's disease (PD), with axonal degeneration preceding the loss of cell ...