These three parallel metabolic pathways work synergistically to suppress phospholipid peroxidation, a hallmark of ferroptosis, by maintaining redox homeostasis and protecting cellular membranes from ...

Improving the safety of hyperoxia therapy has thus become an urgent priority. Ferroptosis, a novel form of regulated cell death characterized by iron accumulation and excessive lipid peroxidation, has ...

推荐阅读：本文聚焦 HNSCC 中 ferroptosis，阐述其分子机制与治疗策略，极具科研价值。 头颈部鳞状细胞癌（HNSCC）中 ferroptosis 的分子机制及治疗研究进展 一、ferroptosis 概述 ferroptosis 是一种受调控的、依赖铁的细胞死亡方式，脂质过氧化和线粒体功能障碍在其中 ...

State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), ChemBioMed Interdisciplinary Research Center, ...

胃癌治疗面临挑战，免疫治疗至关重要。山东大学齐鲁医院研究人员开展关于 Simvastatin 对胃癌细胞作用的研究，发现其可降低血清 ILF3 和 PD-L1 水平，诱导癌细胞铁死亡（Ferroptosis），增强免疫反应，为胃癌免疫联合治疗提供理论依据。 胃癌是全球范围内常见且 ...

Science and Technology Innovation Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250117, China ...

This discovery could lead to breakthrough heart failure treatments. A Japanese research team found that the oxidized form of glutathione (GSSG) may protect heart tissue by modifying a key protein, ...